Holden Karnofsky — History's most important century

Dwarkesh Patel · Beginner ·🛡️ AI Safety & Ethics ·3y ago
Holden Karnofsky is the co-CEO of Open Philanthropy and co-founder of GiveWell. He is also the author of one of the most interesting blogs on the internet, Cold Takes. We discuss: * Are we living in the most important century? * Does he regret OpenPhil’s 30 million dollar grant to OpenAI in 2016? * How does he think about AI, progress, digital people, & ethics? Highly recommend! 𝐄𝐏𝐈𝐒𝐎𝐃𝐄 𝐋𝐈𝐍𝐊𝐒 * Transcript: https://www.dwarkeshpatel.com/p/holden-karnofsky * Spotify: https://spoti.fi/3Qi11SY * Apple Podcasts: https://apple.co/3CmZXav 𝐓𝐈𝐌𝐄𝐒𝐓𝐀𝐌𝐏𝐒 00:00:00 - Intro 00:00:58 - The Most Important Century 00:06:44 - The Weirdness of Our Time 00:21:20 - The Industrial Revolution  00:35:40 - AI Success Scenario 00:52:36 - Competition, Innovation , & AGI Bottlenecks 01:00:14 - Lock-in & Weak Points 01:06:04 - Predicting the Future 01:20:40 - Choosing Which Problem To Solve 01:26:56 - $30M OpenAI Investment 01:30:22 - Future Proof Ethics 01:37:28 - Integrity vs Utilitarianism 01:40:46 - Bayesian Mindset & Governance 01:46:56 - Career Advice
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21 Sam Bankman-Fried - Crypto, FTX, Altruism, & Leadership
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24 Sam Bankman-Fried on GREAT FOUNDERS
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26 Fin Moorhouse - Longtermism, Space, & Entrepreneurship
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31 Charles C. Mann - Americas Before Columbus & Scientific Wizardry
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32 Tyler Cowen - Why Society Will Collapse & Why Sex is Pessimistic
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33 Bryan Caplan - Feminists, Billionaires, and Demagogues
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34 Brian Potter - Future of Construction, Ugly Modernism, & Environmental Review
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35 Kenneth T. Jackson - Robert Moses, Hero of New York?
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36 Edward Glaeser - Cities, Terrorism, Housing, & Remote Work
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37 Byrne Hobart - FTX, Drugs, Twitter, Taiwan, & Monasticism
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38 Nadia Asparouhova — Tech elites, democracy, open source, & philanthropy
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39 Bethany McLean — Enron, FTX, 2008, Musk, frauds, & visionaries
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Holden Karnofsky — History's most important century
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41 $30m Grant to OpenAI?
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42 Does GPT Have Holden Worried?
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43 Lars Doucet — Progress, poverty, Georgism, & why rent is too damn high
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45 Garett Jones — Immigration, national IQ, & less democracy
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46 Marc Andreessen — AI, crypto, 1000 Elon Musks, regrets, vulnerabilities, & managerial revolution
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48 The Future Of Venture Capital
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50 Brett Harrison — FTX US former president speaks out
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51 Nat Friedman (Github CEO) — Reading ancient scrolls, open source, & AI
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52 Ilya Sutskever (OpenAI Chief Scientist) — Why next-token prediction could surpass human intelligence
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53 Impact of Taiwan Invasion on AI
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54 Reliability is Bottleneck on AI - OpenAI Founder
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56 Harmful Uses of GPT - OpenAI Founder
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57 Why OpenAI Founder Thinks AI Is Near
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Chapters (14)

Intro
0:58 The Most Important Century
6:44 The Weirdness of Our Time
21:20 The Industrial Revolution
35:40 AI Success Scenario
52:36 Competition, Innovation , & AGI Bottlenecks
1:00:14 Lock-in & Weak Points
1:06:04 Predicting the Future
1:20:40 Choosing Which Problem To Solve
1:26:56 $30M OpenAI Investment
1:30:22 Future Proof Ethics
1:37:28 Integrity vs Utilitarianism
1:40:46 Bayesian Mindset & Governance
1:46:56 Career Advice
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