Pillar #2: Drug Utilization - Drivers and Consequences

The determinants of drug utilization are complex and multifactorial, and understanding how, why, when and where drugs are used is crucial to inform regulatory and payment policy and clinical practice. We begin by reviewing methods of investigating drug utilization and evaluating interventions to prescribing. We then explore common challenges to optimizing medicine use, including non-adherence and off-label drug use. We also consider methods to improve the quality of drug utilization, including value-based insurance designs, audit and feedback, patient education and medication therapy managem…