AlphaFold and the Grand Challenge to solve protein folding

arXiv Insights · Advanced ·📄 Research Papers Explained ·4y ago
If you want to support this channel, here is my patreon link: https://patreon.com/ArxivInsights --- You are amazing!! ;) If you have questions you would like to discuss with me personally, you can book a 1-on-1 video call through Pensight: https://pensight.com/x/xander-steenbrugge -------------------------------- AlphaFold is DeepMinds latest breakthrough addressing the protein folding problem. Using an advanced Deep Learning architecture that achieves end-to-end learning of protein structures, this work is arguably one of the most influential papers of this decade and is likely to spark en…
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Chapters (9)

Intro
2:28 The Protein Folding Problem
5:29 AlphaFold1 revisited
6:10 Multiple Sequence Alignments (MSA)
8:10 Distograms
12:29 AlphaFold2
14:52 The Evoformer
19:07 The Structure Module
28:13 Zooming out: looking at the future
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