Genetic Underpinnings of Synaptic Disease

This course explores how genetic variation shapes synaptic function, neural circuits, and behavior. Learners will examine how specific gene mutations alter communication between neurons and how these molecular changes scale up to influence cognition, development, and addiction. The course begins by investigating genetic disruptions of synaptic proteins using Fragile X syndrome as a central example. Learners will explore how mutations in key regulatory genes impair synaptic plasticity, alter neural development, and contribute to neurological symptoms, while also examining current challenges an…