Towards Autonomous Mechanistic Reasoning in Virtual Cells

arXiv:2604.11661v1 Announce Type: cross Abstract: Large language models (LLMs) have recently gained significant attention as a promising approach to accelerate scientific discovery. However, their application in open-ended scientific domains such as biology remains limited, primarily due to the lack of factually grounded and actionable explanations. To address this, we introduce a structured explanation formalism for virtual cells that represents biological reasoning as mechanistic action graphs