Rhizome OS-1: Rhizome's Semi-Autonomous Operating System for Small Molecule Drug Discovery

arXiv:2604.07512v2 Announce Type: replace Abstract: We present Rhizome OS-1, a semi-autonomous operating system for small molecule drug discovery in which multi-modal AI agents operate as a full multidisciplinary discovery team. These agents function as computational chemists, medicinal chemists, and patent agents: they write and execute analysis code (fingerprint clustering, R-group decomposition, substructure search), visually triage molecular grids using vision capabilities, formulate explici