Questions Regarding nnU-Net

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I would like to ask a few questions regarding the nnU-Net framework. What is nnU-Net, and which preprocessing steps are automatically performed by the framework? Does nnU-Net automatically apply: Spatial normalization, Intensity normalization, Image resizing/resampling, Any other preprocessing operations? What is the difference between U-Net and nnU-Net? Thank you for your time and assistance. <!-

Published 24 Jun 2026

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