Neuro-Oracle: A Trajectory-Aware Agentic RAG Framework for Interpretable Epilepsy Surgical Prognosis

arXiv:2604.14216v1 Announce Type: cross Abstract: Predicting post-surgical seizure outcomes in pharmacoresistant epilepsy is a clinical challenge. Conventional deep-learning approaches operate on static, single-timepoint pre-operative scans, omitting longitudinal morphological changes. We propose \emph{Neuro-Oracle}, a three-stage framework that: (i) distils pre-to-post-operative MRI changes into a compact 512-dimensional trajectory vector using a 3D Siamese contrastive encoder; (ii) retrieves h