Chronological Contrastive Learning: Few-Shot Progression Assessment in Irreversible Diseases

arXiv:2603.21935v2 Announce Type: replace-cross Abstract: Quantitative disease severity scoring in medical imaging is costly, time-consuming, and subject to inter-reader variability. At the same time, clinical archives contain far more longitudinal imaging data than expert-annotated severity scores. Existing self-supervised methods typically ignore this chronological structure. We introduce ChronoCon, a contrastive learning approach that replaces label-based ranking losses with rankings derived