Eligibility-Aware Evidence Synthesis: An Agentic Framework for Clinical Trial Meta-Analysis

1. 1Identify relevant clinical trials from large registries
2. 2Aggregate results accounting for population differences
3. 3Apply eligibility criteria to weight studies
4. 4Use LLM-based approaches for automated components of systematic review

Data scientists and researchers on a team benefit from this framework as it provides a more accurate and comprehensive approach to clinical trial meta-analysis, while clinicians and medical researchers can apply the results to inform treatment decisions

💡 Conventional meta-analysis can be improved by considering clinical compatibility reflected in eligibility criteria

💡 New framework for clinical trial meta-analysis: Eligibility-Aware Evidence Synthesis #LLMs #MetaAnalysis