DPD-Cancer: Explainable Graph-based Deep Learning for Small Molecule Anti-Cancer Activity Prediction

arXiv:2603.26114v1 Announce Type: cross Abstract: Accurate drug response prediction is a critical bottleneck in computational biochemistry, limited by the challenge of modelling the interplay between molecular structure and cellular context. In cancer research, this is acute due to tumour heterogeneity and genomic variability, which hinder the identification of effective therapies. Conventional approaches often fail to capture non-linear relationships between chemical features and biological out